Home - Congruence

WHAT WE DO

Many diseases are caused by proteins that do not fold correctly or signal properly. We use AI-enabled protein structural information, biology, and chemistry to discover novel small molecules that address disease at its molecular origin, rather than treating symptoms alone.

Key Focus Areas

Congruence is building a pipeline of best-in-class and first-in-class oral small molecule correctors and allosteric modulators directed to genetically validated, difficult-to-drug proteins implicated in diseases spanning a variety of therapeutic areas, including: metabolism, neurology, immunology, oncology and other rare diseases.

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