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Congruence Therapeutics is a clinical-stage biotechnology company that discovers and develops small molecule correctors and allosteric modulators to ameliorate disease conditions at the molecular level.

WHAT WE DO

Many diseases are caused by proteins that do not fold correctly or signal properly. We use AI-enabled protein structural information, biology, and chemistry to discover novel small molecules that address disease at its molecular origin, rather than treating symptoms alone.

Key Focus Areas

Congruence is building a pipeline of best-in-class and first-in-class oral small molecule correctors and allosteric modulators directed to genetically validated, difficult-to-drug proteins implicated in diseases spanning a variety of therapeutic areas, including: metabolism, neurology, immunology, oncology and other rare diseases.

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